Which base pairs with Guanine in DNA?

Guanine is one of the four main nucleobases found in DNA, and it specifically pairs with Cytosine through the formation of three hydrogen bonds. This specific pairing is a fundamental aspect of the structure of DNA, contributing to the stability and integrity of the double helix. The complementary nature of these base pairs is crucial for the accurate replication of DNA during cell division, ensuring that the genetic information is reliably passed on to daughter cells.

In DNA, Adenine pairs with Thymine, not Guanine, while Uracil is found in RNA and does not play a role in DNA base pairing. The pairing rules, known as Chargaff's rules, dictate these specific combinations, emphasizing the importance of Cytosine as the rightful partner to Guanine in the DNA structure.