What is the chromosomal makeup of a male organism?

The chromosomal makeup of a male organism is characterized by the presence of one X chromosome and one Y chromosome, represented as XY. In many species, including humans, this XY configuration is crucial for determining biological sex. The presence of the Y chromosome carries genes that trigger male-specific development and contribute to the formation of male reproductive structures.

In contrast, the XX configuration represents typical female organisms, as they possess two X chromosomes. The YY configuration is not viable in most sexually reproducing organisms, as there is typically no viable organism with two Y chromosomes alone. The XXY configuration is associated with a condition known as Klinefelter syndrome, which results from an extra X chromosome in males and leads to a variety of physical and developmental characteristics, but it still differs from the typical male chromosomal makeup of XY.

Thus, the XY combination distinctly signifies male gender in species where this chromosomal determination is applicable.